A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells.

Transforming growth factor beta (TGF-beta) is a potent inhibitor of epithelial cell growth. Cyclins E and A in association with Cdk2 have been shown to play a role in the G1-to-S phase transition in mammalian cells. We have studied the effects of TGF-beta-mediated growth arrest on G1/S cyclins E and...

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Main Authors: Slingerland, J M, Hengst, L, Pan, C H, Alexander, D, Stampfer, M R, Reed, S I
格式: Artigo
語言:Inglês
出版: 1994
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC358736/
https://ncbi.nlm.nih.gov/pubmed/8196612
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