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A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells.
Transforming growth factor beta (TGF-beta) is a potent inhibitor of epithelial cell growth. Cyclins E and A in association with Cdk2 have been shown to play a role in the G1-to-S phase transition in mammalian cells. We have studied the effects of TGF-beta-mediated growth arrest on G1/S cyclins E and...
Kaydedildi:
Asıl Yazarlar: | , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
1994
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC358736/ https://ncbi.nlm.nih.gov/pubmed/8196612 |
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