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Particle shape enhances specificity of antibody-displaying nanoparticles
Monoclonal antibodies are used in numerous therapeutic and diagnostic applications; however, their efficacy is contingent on specificity and avidity. Here, we show that presentation of antibodies on the surface of nonspherical particles enhances antibody specificity as well as avidity toward their t...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587278/ https://ncbi.nlm.nih.gov/pubmed/23401509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216893110 |
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