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Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation
Endoplasmic reticulum–associated degradation (ERAD) is a constitutive process that identifies misfolded proteins in the ER and shuttles them to the cytosol, where they can be degraded by the proteasome. The accumulation of misfolded proteins can be catastrophic at both the cellular and organismal le...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587246/ https://ncbi.nlm.nih.gov/pubmed/23401531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300328110 |
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