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Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation

Endoplasmic reticulum–associated degradation (ERAD) is a constitutive process that identifies misfolded proteins in the ER and shuttles them to the cytosol, where they can be degraded by the proteasome. The accumulation of misfolded proteins can be catastrophic at both the cellular and organismal le...

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Detalhes bibliográficos
Main Authors: Grotzke, Jeff E., Lu, Qiao, Cresswell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587246/
https://ncbi.nlm.nih.gov/pubmed/23401531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300328110
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