Neto2 is a KCC2 interacting protein required for neuronal Cl(−) regulation in hippocampal neurons

KCC2 is a neuron-specific K(+)–Cl(−) cotransporter that is essential for Cl(−) homeostasis and fast inhibitory synaptic transmission in the mature CNS. Despite the critical role of KCC2 in neurons, the mechanisms regulating its function are not understood. Here, we show that KCC2 is critically regul...

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Autori principali: Ivakine, Evgueni A., Acton, Brooke A., Mahadevan, Vivek, Ormond, Jake, Tang, Man, Pressey, Jessica C., Huang, Michelle Y., Ng, David, Delpire, Eric, Salter, Michael W., Woodin, Melanie A., McInnes, Roderick R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587235/
https://ncbi.nlm.nih.gov/pubmed/23401525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212907110
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