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Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses

Neuroinflammation plays a major role in the pathophysiology of diseases of the central nervous system, and the role of astroglial cells in this process is increasingly recognized. Thrombin and the lysophospholipids lysophosphatidic acid and sphingosine 1-phosphate (S1P) are generated during injury a...

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Detalhes bibliográficos
Main Authors: Dusaban, Stephanie S., Purcell, Nicole H., Rockenstein, Edward, Masliah, Eliezer, Cho, Min Kyung, Smrcka, Alan V., Brown, Joan Heller
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587233/
https://ncbi.nlm.nih.gov/pubmed/23401561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217355110
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