Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer

We reported earlier the delivery of antiangiogenic single chain antibodies by using oncolytic vaccinia virus strains to enhance their therapeutic efficacy. Here, we provide evidence that gene-evoked production of melanin can be used as a therapeutic and diagnostic mediator, as exemplified by inserti...

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Bibliographische Detailangaben
Hauptverfasser: Stritzker, Jochen, Kirscher, Lorenz, Scadeng, Miriam, Deliolanis, Nikolaos C., Morscher, Stefan, Symvoulidis, Panagiotis, Schaefer, Karin, Zhang, Qian, Buckel, Lisa, Hess, Michael, Donat, Ulrike, Bradley, William G., Ntziachristos, Vasilis, Szalay, Aladar A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587225/
https://ncbi.nlm.nih.gov/pubmed/23401518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216916110
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