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Toxicodynamics of Rigid Polystyrene Microparticles on Pulmonary Gas Exchange in Mice: Implications for Microemboli-based Drug Delivery Systems

The toxicodynamic relationship between the number and size of pulmonary microemboli resulting from uniformly sized, rigid polystyrene microparticles (MPs) administered intravenously and their potential effects on pulmonary gas exchange was investigated. CD-1 male mice (6–8 wk) were intravenously adm...

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Detalhes bibliográficos
Main Authors: Kutscher, HL., Gao, D., Li, S., Massa, CB., Cervelli, J., Deshmukh, M., Joseph, LB., Laskin, DL., Sinko, PJ.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586786/
https://ncbi.nlm.nih.gov/pubmed/23142466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.10.021
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