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Toxicodynamics of Rigid Polystyrene Microparticles on Pulmonary Gas Exchange in Mice: Implications for Microemboli-based Drug Delivery Systems

The toxicodynamic relationship between the number and size of pulmonary microemboli resulting from uniformly sized, rigid polystyrene microparticles (MPs) administered intravenously and their potential effects on pulmonary gas exchange was investigated. CD-1 male mice (6–8 wk) were intravenously adm...

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Bibliographische Detailangaben
Hauptverfasser: Kutscher, HL., Gao, D., Li, S., Massa, CB., Cervelli, J., Deshmukh, M., Joseph, LB., Laskin, DL., Sinko, PJ.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586786/
https://ncbi.nlm.nih.gov/pubmed/23142466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.10.021
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