The NRF2-heme oxygenase-1 system modulates cyclosporine A-induced epithelial-mesenchymal transition and renal fibrosis

Epithelial-mesenchymal transition (EMT) is an underlying mechanism of tissue fibrosis by generating myofibroblasts, which serve as the primary source of extracellular matrix production from tissue epithelial cells. Recently, it has been suggested that EMT is implicated in immunosuppressive cyclospor...

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Autors principals: Shin, Dong-ha, Park, Hyun-Min, Jung, Kyeong-Ah, Choi, Han-Gon, Kim, Jung-Ae, Kim, Dae-Duk, Kim, Sang Geon, Kang, Keon Wook, Ku, Sae Kwang, Kensler, Thomas W., Kwak, Mi-Kyoung
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586736/
https://ncbi.nlm.nih.gov/pubmed/20096777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.021
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