Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signalling dynamics

Co-immunoprecipitation (co-IP) has become a standard technique, but its protein-band output provides only static, qualitative information about protein–protein interactions. Here we demonstrate a real-time single-molecule co-IP technique that generates real-time videos of individual protein–protein...

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Detalhes bibliográficos
Main Authors: Lee, Hong-Won, Kyung, Taeyoon, Yoo, Janghyun, Kim, Tackhoon, Chung, Chaeuk, Ryu, Ji Young, Lee, Hanki, Park, Kihyun, Lee, Sangkyu, Jones, Walton D., Lim, Dae-Sik, Hyeon, Changbong, Do Heo, Won, Yoon, Tae-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586730/
https://ncbi.nlm.nih.gov/pubmed/23422673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2507
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