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Maintaining Mammalian Iron and Oxygen Homeostasis: Sensors, Regulation, and Cross-Talk

Though iron and oxygen are required to sustain essential biological processes, an excess of either can result in oxidative stress. Therefore, mammals tightly regulate cellular and systemic iron and oxygen homeostasis. At the cellular level, the hypoxia-inducible transcription factors (HIFs) are key...

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Autori principali: Salahudeen, Ameen A., Bruick, Richard K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586564/
https://ncbi.nlm.nih.gov/pubmed/19845604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05038.x
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