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UVA Phototransduction Drives Early Melanin Synthesis in Human Melanocytes
Exposure of human skin to solar ultraviolet radiation (UVR), a powerful carcinogen [1] comprising ~95% UVA and ~5% UVB at the Earth’s surface, promotes melanin synthesis in epidermal melanocytes [2, 3], which protects skin from DNA damage [4, 5]. UVB causes DNA lesions [6] that lead to transcription...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586554/ https://ncbi.nlm.nih.gov/pubmed/22055294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.09.047 |
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