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UVA Phototransduction Drives Early Melanin Synthesis in Human Melanocytes

Exposure of human skin to solar ultraviolet radiation (UVR), a powerful carcinogen [1] comprising ~95% UVA and ~5% UVB at the Earth’s surface, promotes melanin synthesis in epidermal melanocytes [2, 3], which protects skin from DNA damage [4, 5]. UVB causes DNA lesions [6] that lead to transcription...

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Bibliografische gegevens
Hoofdauteurs: Wicks, Nadine L., Chan, Jason W., Najera, Julia A., Ciriello, Jonathan M., Oancea, Elena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586554/
https://ncbi.nlm.nih.gov/pubmed/22055294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.09.047
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