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Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen.

The ability of simian virus 40-encoded large T antigen to disrupt the growth control of a variety of cell types is related to its ability to interfere with certain cellular proteins, such as p53 and the retinoblastoma susceptibility gene product (pRB). We have used wild-type and mutant forms of T an...

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Bibliografiska uppgifter
Huvudupphovsmän: Sáenz Robles, M T, Symonds, H, Chen, J, Van Dyke, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC358635/
https://ncbi.nlm.nih.gov/pubmed/8139568
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