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Stereochemically Probing the photo-Favorskii Rearrangement: A Mechanistic Investigation

Using model (R)-2-acetyl-2-phenyl acetate esters of (S)- or (R)-α-substituted-p-hydroxybutyrophenones (S,R)-12a and (R,R)-12b, we have shown that a highly efficient photo-Favorskii rearrangement proceeds through a series of intermediates to form racemic rearrangement products. The stereogenic methin...

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Main Authors: Givens, Richard S., Rubina, Marina, Stensrud, Kenneth F.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586294/
https://ncbi.nlm.nih.gov/pubmed/23057737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo301640q
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