Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron.

Translational control of the GCN4 gene in response to amino acid availability is mediated by four short open reading frames in the GCN4 mRNA leader (uORFs) and by phosphorylation of eukaryotic initiation factor 2 (eIF-2). We have proposed that reducing eIF-2 activity by phosphorylation of its alpha...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Grant, C M, Miller, P F, Hinnebusch, A G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2616-2628.1994
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