Comprehensive Analysis of BRCA1, BRCA2 and TP53 Germline Mutation and Tumor Characterization: A Portrait of Early-Onset Breast Cancer in Brazil

Germline mutations in BRCA1, BRCA2 and TP53 genes have been identified as one of the most important disease-causing issues in young breast cancer patients worldwide. The specific defective biological processes that trigger germline mutation-associated and -negative tumors remain unclear. To delineat...

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Hauptverfasser: Carraro, Dirce Maria, Koike Folgueira, Maria Aparecida Azevedo, Garcia Lisboa, Bianca Cristina, Ribeiro Olivieri, Eloisa Helena, Vitorino Krepischi, Ana Cristina, de Carvalho, Alex Fiorini, de Carvalho Mota, Louise Danielle, Puga, Renato David, do Socorro Maciel, Maria, Michelli, Rodrigo Augusto Depieri, de Lyra, Eduardo Carneiro, Grosso, Stana Helena Giorgi, Soares, Fernando Augusto, de Souza Waddington Achatz, Maria Isabel Alves, Brentani, Helena, Moreira-Filho, Carlos Alberto, Brentani, Maria Mitzi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586086/
https://ncbi.nlm.nih.gov/pubmed/23469205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057581
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