Li-Fraumeni-like syndrome associated with a large BRCA1 intragenic deletion

BACKGROUND: Li-Fraumeni (LFS) and Li-Fraumeni-like (LFL) syndromes are associated to germline TP53 mutations, and are characterized by the development of central nervous system tumors, sarcomas, adrenocortical carcinomas, and other early-onset tumors. Due to the high frequency of breast cancer in LF...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Silva, Amanda Gonçalves, Ewald, Ingrid Petroni, Sapienza, Marina, Pinheiro, Manuela, Peixoto, Ana, de Nóbrega, Amanda França, Carraro, Dirce M, Teixeira, Manuel R, Ashton-Prolla, Patricia, Achatz, Maria Isabel W, Rosenberg, Carla, Krepischi, Ana C V
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502571/
https://ncbi.nlm.nih.gov/pubmed/22691290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-237
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi