Kinetic Characterization of PB1-F2-Mediated Immunopathology during Highly Pathogenic Avian H5N1 Influenza Virus Infection

The PB1-F2 protein encoded by influenza A viruses can contribute to virulence, a feature that is dependent of its sequence polymorphism. Whereas PB1-F2 from some H1N1 viruses were shown to exacerbate the inflammatory response within the airways, the contribution of PB1-F2 to highly pathogenic avian...

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Main Authors: Leymarie, Olivier, Jouvion, Grégory, Hervé, Pierre-Louis, Chevalier, Christophe, Lorin, Valérie, Lecardonnel, Jérôme, Da Costa, Bruno, Delmas, Bernard, Escriou, Nicolas, Le Goffic, Ronan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585811/
https://ncbi.nlm.nih.gov/pubmed/23469251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057894
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