Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha components.

Ítems similars

• Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.
  per: Pine, R, et al.
  Publicat: (1994)
• Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons.
  per: John, J, et al.
  Publicat: (1991)
• High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons.
  per: McKendry, R, et al.
  Publicat: (1991)
• Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon.
  per: Moskophidis, D, et al.
  Publicat: (1994)
• Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation.
  per: Nicholson, S E, et al.
  Publicat: (1994)