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Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors.

Interleukin-2 (IL-2) transcription is developmentally restricted to T cells and physiologically dependent on specific stimuli such as antigen recognition. Prior studies have shown that this stringent two-tiered regulation is mediated through a transcriptional promoter/enhancer DNA segment which is c...

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Autors principals: Garrity, P A, Chen, D, Rothenberg, E V, Wold, B J
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC358576/
https://ncbi.nlm.nih.gov/pubmed/8114746
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