A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

The maintenance of pluripotency in mouse embryonic stem cells (mESCs) relies on the activity of a transcriptional network that is fuelled by the activity of three transcription factors (Nanog, Oct4 and Sox2) and balanced by the repressive activity of Tcf3. Extracellular signals modulate the activity...

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Main Authors: Faunes, Fernando, Hayward, Penelope, Descalzo, Silvia Muñoz, Chatterjee, Sujash S., Balayo, Tina, Trott, Jamie, Christoforou, Andrew, Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Dasgupta, Ramanuj, Arias, Alfonso Martinez
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2013
Fag:
Development and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585656/
https://ncbi.nlm.nih.gov/pubmed/23444350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.085654
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