Src binds cortactin through an SH2 domain cystine-mediated linkage

Tyrosine-kinase-based signal transduction mediated by modular protein domains is critical for cellular function. The Src homology (SH)2 domain is an important conductor of intracellular signaling that binds to phosphorylated tyrosines on acceptor proteins, producing molecular complexes responsible f...

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Bibliografiske detaljer
Main Authors: Evans, Jason V., Ammer, Amanda G., Jett, John E., Bolcato, Chris A., Breaux, Jason C., Martin, Karen H., Culp, Mark V., Gannett, Peter M., Weed, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585525/
https://ncbi.nlm.nih.gov/pubmed/23097045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.121046
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