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Clinical and Biological Relevance of Genomic Heterogeneity in Chronic Lymphocytic Leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is typically regarded as an indolent B-cell malignancy. However, there is wide variability with regards to need for therapy, time to progressive disease, and treatment response. This clinical variability is due, in part, to biological heterogeneity betw...

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Detalhes bibliográficos
Main Authors: Friedman, Daphne R., Lucas, Joseph E., Weinberg, J. Brice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585365/
https://ncbi.nlm.nih.gov/pubmed/23468975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057356
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