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Clinical and Biological Relevance of Genomic Heterogeneity in Chronic Lymphocytic Leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is typically regarded as an indolent B-cell malignancy. However, there is wide variability with regards to need for therapy, time to progressive disease, and treatment response. This clinical variability is due, in part, to biological heterogeneity betw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Friedman, Daphne R., Lucas, Joseph E., Weinberg, J. Brice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585365/
https://ncbi.nlm.nih.gov/pubmed/23468975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057356
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