Point mutations in the stem-loop at the 3' end of mouse histone mRNA reduce expression by reducing the efficiency of 3' end formation.

Mammalian histone mRNAs end in a highly conserved stem-loop structure, with a six-base stem and a four-base loop. We have examined the effect of mutating the stem-loop on the expression of the histone mRNA in vivo by introducing the mutated histone genes into CHO cells by stable transfection. Point...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Pandey, N B, Williams, A S, Sun, J H, Brown, V D, Bond, U, Marzluff, W F
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8114706/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.3.1709
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires