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Point mutations in the stem-loop at the 3' end of mouse histone mRNA reduce expression by reducing the efficiency of 3' end formation.

Mammalian histone mRNAs end in a highly conserved stem-loop structure, with a six-base stem and a four-base loop. We have examined the effect of mutating the stem-loop on the expression of the histone mRNA in vivo by introducing the mutated histone genes into CHO cells by stable transfection. Point...

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Detaylı Bibliyografya
Asıl Yazarlar: Pandey, N B, Williams, A S, Sun, J H, Brown, V D, Bond, U, Marzluff, W F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC358529/
https://ncbi.nlm.nih.gov/pubmed/8114706
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