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Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance

Rap1 and Rap2 are closely related proteins of the Ras family of small G-proteins. Rap1 is well known to regulate cell-cell adhesion. Here, we have analysed the effect of Rap-mediated signalling on endothelial permeability using electrical impedance measurements of HUVEC monolayers and subsequent det...

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Detalhes bibliográficos
Main Authors: Pannekoek, Willem-Jan, Linnemann, Jelena R., Brouwer, Patricia M., Bos, Johannes L., Rehmann, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585282/
https://ncbi.nlm.nih.gov/pubmed/23469100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057903
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