Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29

Rap1 is a small GTPase regulating cell–cell adhesion, cell–matrix adhesion, and actin rearrangements, all processes dynamically coordinated during cell spreading and endothelial barrier function. Here, we identify the adaptor protein ras-interacting protein 1 (Rasip1) as a Rap1-effector involved in...

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Bibliographic Details
Main Authors: Post, Anneke, Pannekoek, Willem-Jan, Ross, Sarah H., Verlaan, Ingrid, Brouwer, Patricia M., Bos, Johannes L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710801/
https://ncbi.nlm.nih.gov/pubmed/23798437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306595110
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