Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

The phosphorylation of protein tyrosine kinases (PTKs) on tyrosine residues is a critical regulatory event that modulates catalytic activity and triggers the physical association of PTKs with Src homology 2 (SH2)-containing proteins. The integrin-linked focal adhesion kinase, pp125FAK, exhibits extr...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Schaller, M D, Hildebrand, J D, Shannon, J D, Fox, J W, Vines, R R, Parsons, J T
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.3.1680-1688.1994
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