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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

The phosphorylation of protein tyrosine kinases (PTKs) on tyrosine residues is a critical regulatory event that modulates catalytic activity and triggers the physical association of PTKs with Src homology 2 (SH2)-containing proteins. The integrin-linked focal adhesion kinase, pp125FAK, exhibits extr...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Schaller, M D, Hildebrand, J D, Shannon, J D, Fox, J W, Vines, R R, Parsons, J T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.3.1680-1688.1994
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