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The heparin-binding domain of amphiregulin necessitates the precursor pro-region for growth factor secretion.

The five members of the human epidermal growth factor (EGF) family (EGF, transforming growth factor alpha [TGF-alpha], heparin-binding EGF-like growth factor [HB-EGF], betacellulin, and amphiregulin [AR]) are synthesized as transmembrane proteins whose extracellular domains are proteolytically proce...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Thorne, B A, Plowman, G D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8114701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.3.1635
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