Sustained Activation of Akt Elicits Mitochondrial Dysfunction to Block Plasmodium falciparum Infection in the Mosquito Host

The overexpression of activated, myristoylated Akt in the midgut of female transgenic Anopheles stephensi results in resistance to infection with the human malaria parasite Plasmodium falciparum but also decreased lifespan. In the present study, the understanding of mitochondria-dependent midgut hom...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Luckhart, Shirley, Giulivi, Cecilia, Drexler, Anna L., Antonova-Koch, Yevgeniya, Sakaguchi, Danielle, Napoli, Eleonora, Wong, Sarah, Price, Mark S., Eigenheer, Richard, Phinney, Brett S., Pakpour, Nazzy, Pietri, Jose E., Cheung, Kong, Georgis, Martha, Riehle, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585164/
https://ncbi.nlm.nih.gov/pubmed/23468624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003180
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы