Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth

Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subset of HIV-1 infected subjects during chronic infection. Exact mechanisms that expand the otherwise narrow neutralization capacity observed during early infection are, however, currently undefined. Here...

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Main Authors: Murphy, Megan K., Yue, Ling, Pan, Ruimin, Boliar, Saikat, Sethi, Anurag, Tian, Jianhui, Pfafferot, Katja, Karita, Etienne, Allen, Susan A., Cormier, Emmanuel, Goepfert, Paul A., Borrow, Persephone, Robinson, James E., Gnanakaran, S., Hunter, Eric, Kong, Xiang-Peng, Derdeyn, Cynthia A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585129/
https://ncbi.nlm.nih.gov/pubmed/23468623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003173
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