Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth

Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subset of HIV-1 infected subjects during chronic infection. Exact mechanisms that expand the otherwise narrow neutralization capacity observed during early infection are, however, currently undefined. Here...

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Detalhes bibliográficos
Main Authors: Murphy, Megan K., Yue, Ling, Pan, Ruimin, Boliar, Saikat, Sethi, Anurag, Tian, Jianhui, Pfafferot, Katja, Karita, Etienne, Allen, Susan A., Cormier, Emmanuel, Goepfert, Paul A., Borrow, Persephone, Robinson, James E., Gnanakaran, S., Hunter, Eric, Kong, Xiang-Peng, Derdeyn, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585129/
https://ncbi.nlm.nih.gov/pubmed/23468623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003173
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