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Gadd45a Suppresses Tumor Angiogenesis via Inhibition of the mTOR/STAT3 Protein Pathway

Gadd45a, a p53-regulated and DNA damage-inducible gene, is implicated in protection against tumor malignancy, although the underlying mechanism remains to be defined further. Here we demonstrate that Gadd45a plays an important role in suppression of tumor angiogenesis. Gadd45a deletion significantly...

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Bibliografski detalji
Glavni autori: Yang, Fang, Zhang, Weimin, Li, Dan, Zhan, Qimin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585088/
https://ncbi.nlm.nih.gov/pubmed/23329839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418335
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