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Suppression of Viral Replication by Stress-Inducible GADD34 Protein via the Mammalian Serine/Threonine Protein Kinase mTOR Pathway

GADD34 is a protein that is induced by a variety of stressors, including DNA damage, heat shock, nutrient deprivation, energy depletion, and endoplasmic reticulum stress. Here, we demonstrated that GADD34 induced by vesicular stomatitis virus (VSV) infection suppressed viral replication in wild-type...

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Detalhes bibliográficos
Main Authors: Minami, Kahori, Tambe, Yukihiro, Watanabe, Ryosuke, Isono, Takahiro, Haneda, Masataka, Isobe, Ken-ichi, Kobayashi, Toshiyuki, Hino, Okio, Okabe, Hidetoshi, Chano, Tokuhiro, Inoue, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045534/
https://ncbi.nlm.nih.gov/pubmed/17670836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01063-07
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