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Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans

The normal aging process is associated with stereotyped changes in gene expression, but the regulators responsible for these age-dependent changes are poorly understood. Using a novel genomics approach, we identified HOX co-factor unc-62 (Homothorax) as a developmental regulator that binds proximal...

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Detalhes bibliográficos
Main Authors: Van Nostrand, Eric L., Sánchez-Blanco, Adolfo, Wu, Beijing, Nguyen, Andy, Kim, Stuart K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585033/
https://ncbi.nlm.nih.gov/pubmed/23468654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003325
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