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JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

Retrograde axonal transport requires an intricate interaction between the dynein motor and its cargo. What mediates this interaction is largely unknown. Using forward genetics and a novel in vivo imaging approach, we identified JNK-interacting protein 3 (Jip3) as a direct mediator of dynein-based re...

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Bibliographic Details
Main Authors: Drerup, Catherine M., Nechiporuk, Alex V.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585007/
https://ncbi.nlm.nih.gov/pubmed/23468645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003303
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