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High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes: correlation with binding sites for transcription factors.

DNA methylation within GC-rich promoters of constitutively expressed X-linked genes is correlated with transcriptional silencing on the inactive X chromosome in female mammals. For most X-linked genes, X chromosome inactivation results in transcriptionally active and inactive alleles occupying each...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Hornstra, I K, Yang, T P
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.2.1419-1430.1994
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