De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia

OBJECTIVES: We describe the antimicrobial activity against Pseudomonas aeruginosa of the de novo-derived antimicrobial peptide WLBU2 in an animal model of infection. METHODS: For this study, an intravenous (iv) model of P. aeruginosa infection was established. The minimum lethal murine dose of P. ae...

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Hlavní autoři: Deslouches, Berthony, Gonzalez, Ivan A., DeAlmeida, Dilhari, Islam, Kazi, Steele, Chad, Montelaro, Ronald C., Mietzner, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584960/
https://ncbi.nlm.nih.gov/pubmed/17623696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkm253
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