Homology-based inference sets the bar high for protein function prediction

BACKGROUND: Any method that de novo predicts protein function should do better than random. More challenging, it also ought to outperform simple homology-based inference. METHODS: Here, we describe a few methods that predict protein function exclusively through homology. Together, they set the bar o...

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Hlavní autoři: Hamp, Tobias, Kassner, Rebecca, Seemayer, Stefan, Vicedo, Esmeralda, Schaefer, Christian, Achten, Dominik, Auer, Florian, Boehm, Ariane, Braun, Tatjana, Hecht, Maximilian, Heron, Mark, Hönigschmid, Peter, Hopf, Thomas A, Kaufmann, Stefanie, Kiening, Michael, Krompass, Denis, Landerer, Cedric, Mahlich, Yannick, Roos, Manfred, Rost, Burkhard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Proceedings
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584931/
https://ncbi.nlm.nih.gov/pubmed/23514582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S3-S7
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