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Mycobacterial Trehalose Dimycolate Reprograms Macrophage Global Gene Expression and Activates Matrix Metalloproteinases
Trehalose 6,6′-dimycolate (TDM) is a cell wall glycolipid and an important virulence factor of mycobacteria. In order to study the role of TDM in the innate immune response to Mycobacterium tuberculosis, microarray analysis was used to examine gene regulation in murine bone marrow-derived macrophage...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Microbiology
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584883/ https://ncbi.nlm.nih.gov/pubmed/23264051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00906-12 |
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