Mycobacterial Trehalose Dimycolate Reprograms Macrophage Global Gene Expression and Activates Matrix Metalloproteinases

Trehalose 6,6′-dimycolate (TDM) is a cell wall glycolipid and an important virulence factor of mycobacteria. In order to study the role of TDM in the innate immune response to Mycobacterium tuberculosis, microarray analysis was used to examine gene regulation in murine bone marrow-derived macrophage...

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Detalhes bibliográficos
Main Authors: Sakamoto, Kaori, Kim, Mi Jeong, Rhoades, Elizabeth R., Allavena, Rachel E., Ehrt, Sabine, Wainwright, Helen C., Russell, David G., Rohde, Kyle H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584883/
https://ncbi.nlm.nih.gov/pubmed/23264051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00906-12
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