The Unique Structure of Haemophilus influenzae Protein E Reveals Multiple Binding Sites for Host Factors

Haemophilus influenzae protein E (PE) is a multifunctional adhesin involved in direct interactions with lung epithelial cells and host proteins, including plasminogen and the extracellular matrix proteins vitronectin and laminin. We recently crystallized PE and successfully collected X-ray diffracti...

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Autori principali: Singh, Birendra, Al-Jubair, Tamim, Mörgelin, Matthias, Thunnissen, Marjolein M., Riesbeck, Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584867/
https://ncbi.nlm.nih.gov/pubmed/23275089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01111-12
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