Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins.

Tumor-specific activation of the TAL1 gene is the most common genetic alteration seen in patients with T-cell acute lymphoblastic leukemia. The TAL1 gene products contain the basic helix-loop-helix (bHLH) domain, a protein dimerization and DNA-binding motif common to several known transcription fact...

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Autores principales: Hsu, H L, Huang, L, Tsan, J T, Funk, W, Wright, W E, Hu, J S, Kingston, R E, Baer, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC358481/
https://ncbi.nlm.nih.gov/pubmed/8289805
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