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In-Source Fragmentation and the Sources of Partially Tryptic Peptides in Shotgun Proteomics

Partially tryptic peptides are often identified in shotgun proteomics using trypsin as the proteolytic enzyme; however, their sources have been controversial. Herein we investigate the impact of in-source fragmentation on shotgun proteomics profiling of three biological samples: a standard protein m...

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Autori principali: Kim, Jong-Seo, Monroe, Matthew E., Camp, David G., Smith, Richard D., Qian, Wei-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584699/
https://ncbi.nlm.nih.gov/pubmed/23268687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300955f
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