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The impact of amidination on peptide fragmentation and identification in shotgun proteomics
Peptide amidination labeling using S-methyl thioacetimidate (SMTA) is investigated in an attempt to increase the number and types of peptides that can be detected in a bottom-up proteomics experiment. This derivatization method affects the basicity of lysine residues, and is shown here to significan...
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| Publicat a: | J Proteome Res |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767123/ https://ncbi.nlm.nih.gov/pubmed/27615690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00468 |
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