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The impact of amidination on peptide fragmentation and identification in shotgun proteomics

Peptide amidination labeling using S-methyl thioacetimidate (SMTA) is investigated in an attempt to increase the number and types of peptides that can be detected in a bottom-up proteomics experiment. This derivatization method affects the basicity of lysine residues, and is shown here to significan...

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Bibliografski detalji
Izdano u:J Proteome Res
Glavni autori: Li, Sujun, Dabir, Aditi, Misal, Santosh A., Tang, Haixu, Radivojac, Predrag, Reilly, James P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767123/
https://ncbi.nlm.nih.gov/pubmed/27615690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00468
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