Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.

The Ras(17N) dominant negative antagonizes endogenous Ras function by forming stable, inactive complexes with Ras guanine nucleotide exchange factors (GEFs; e.g., SOS1). We have used the growth-inhibitory phenotype of Ras(17N) to characterize two aspects of Ras interaction with GEFs. First, we used...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Quilliam, L A, Kato, K, Rabun, K M, Hisaka, M M, Huff, S Y, Campbell-Burk, S, Der, C J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC358467/
https://ncbi.nlm.nih.gov/pubmed/8289792
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk