Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression.
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription in the islet is the concentration of circulating glucose. Previous studies have demonstrated that transcription is regulated by the binding of trans-acting factors to speci...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1994
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.2.871-879.1994 |
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