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A Metabolic Prototype for Eliminating Tryptophan From The Genetic Code
We set out to reduce the chemical constitution of a living organism to 19 amino acids. A strain was constructed for reassigning the tryptophan codon UGG to histidine and eliminating tryptophan from Escherichia coli. Histidine codons in the gene for an essential enzyme were replaced with tryptophan c...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584311/ https://ncbi.nlm.nih.gov/pubmed/23447021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01359 |
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